WebCyclophosphamide là tác nhân alkyl hóa và có trong họ thuốc mù tạt. Người ta cho rằng nó hoạt động bằng cách can thiệp vào quá trình sao chép DNA và tổng hợp RNA. … WebCHEBI:4027 - cyclophosphamide. A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom. This entity has been manually annotated by the ChEBI Team. We are unable to retrieve the vendor information for this entry at this time.

mesna [TUSOM Pharmwiki]

WebMay 6, 2024 · This immunologic mismatch can also lead to lethal graft-versus-host disease (GVHD), and immunosuppression strategies, including high-dose posttransplantation cyclophosphamide (PTCy), have been developed to allow for safe alloHSCT delivery. Cyclophosphamide (CP), also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and … See more Cyclophosphamide is used to treat cancers and autoimmune diseases. It is used to quickly control the disease. Due to its toxicity, it is replaced as soon as possible by less toxic drugs. Regular and frequent laboratory … See more Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) except for life-threatening … See more Oral cyclophosphamide is rapidly absorbed and then converted by mixed-function oxidase enzymes (cytochrome P450 system) in the liver to active metabolites. The main active metabolite is 4-hydroxycyclophosphamide, which exists in See more As reported by O. M. Colvin in his study of the development of cyclophosphamide and its clinical applications, Phosphoramide mustard, one of the principal toxic metabolites of cyclophosphamide, was synthesized and reported by … See more Adverse drug reactions from cyclophosphamide are related to the cumulative medication dose and include chemotherapy-induced nausea and vomiting, bone marrow suppression, stomach ache, hemorrhagic cystitis, diarrhea, … See more The main effect of cyclophosphamide is due to its metabolite phosphoramide mustard. This metabolite is only formed in cells that have low … See more The abbreviation CP is common, although abbreviating drug names is not best practice in medicine. See more small unfinished wooden boxes bulk

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WebCyclophosphamide (Cytoxan) (irritant or neutral, depending on reference) Cytarabine (Ara-C) (irritant or neutral, depending on reference) Fludarabine (Fludara) Gemcitabine (Gemzar) (irritant or neutral, depending on reference) Ifosfamide (Ifex) (irritant or … WebHemorrhagic cystitis or haemorrhagic cystitis is an inflammation of the bladder defined by lower urinary tract symptoms that include dysuria, hematuria, and hemorrhage. The disease can occur as a complication of cyclophosphamide, ifosfamide and radiation therapy. WebCyclophosphamide, an orally active alkylating agent, is widely used to treat a variety of malignant and nonmalignant disorders. Although it has some tumour selectivity, it also possesses a wide spectrum of toxicities. The requirement of metabolic activation before cyclophosphamide exerts either its … Cyclophosphamide toxicity. Drugs. small unfinished wooden boxes wholesale