Dab2 interacting protein

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August undefined, 2024

WebDownload scientific diagram Identi®cation of Dvl-3 as a Dab2-interacting protein. ( A ) Schematic representation of the small-pool cDNA screening strategy using GST±PID. ( B ) Schematic ... WebFeb 15, 2024 · Abstract. Disabled-2 (Dab2/DOC-2) is a mitogen-responsive adaptor protein required for multiple cellular functions. It is involved in many signaling pathways and plays an integral role in vesicular uptake and trafficking, modulating immune function, protein …

DAB2 - Wikipedia

WebSep 1, 2024 · DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP. mRNA was down-regulated and inversely correlated with miR-1307-3p level in HCC tissues ... WebASK1-interacting protein-1 (AIP1) is a newly discovered signal scaffold protein, which is a member of the Ras-GTPase activating protein (Ras-GAP) family. 8 The expression of AIP1 in tumor cells is inhibited by histone-lysine N-methyltransferase EZH2 protein, 9,10 which is highly expressed in various tumor tissues and functions to promote the ... cpt code ct of abdomen with contrast

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WebApr 1, 2012 · This indicates that the interaction between Dab2 and a DPF-interacting protein is essential for Dab2 function when AP2 levels are low. This DPF-interacting protein is likely FCHO2. While this requirement is only revealed under artificial conditions, its discovery adds to the understanding of the complex interactions occurring within a … http://www.cancerindex.org/geneweb/DAB2.htm WebOct 4, 2016 · By interacting with other cellular factors through these motifs, Dab2 elicits its functions in endocytosis, differentiation, and immune response and is involved in the cell signaling pathways of Ras-mitogen activated protein kinase (MAPK), Wnt, TGF-β, c-Src and RhoA-ROCK [24, 27–36]. distance from harare to chinhoyi

Differential Regulation of the Human Gene DAB2IP in Normal and ...

The adaptor protein Disabled-2: new insights into ... - SpringerLink

WebFeb 9, 2012 · This indicates that the interaction between Dab2 and a DPF-interacting protein is essential for Dab2 function when AP2 levels are low. This DPF-interacting … WebDab2IP, also known as apoptosis signal-regulating kinase-interacting protein-1 (ASK1), is a GTPase activating protein associated with aggressive metastatic prostate cancer , … cpt code ct pelvis woWebMar 21, 2024 · DAB2 (DAB Adaptor Protein 2) is a Protein Coding gene. Diseases associated with DAB2 include Teratocarcinoma and Hypercholesterolemia, Familial, 4 . … distance from harare to chishawasha

"WebNov 18, 2016 · The cytoplasmic Ras-GAP protein DAB2IP (Disabled-2 Interacting Protein) is a negative modulator of multiple oncogenic pathways. DAB2IP is rarely mutated, but frequently downregulated or ... " - Dab2 interacting protein

Dab2 interacting protein

DAB2IP Gene - GeneCards DAB2P Protein DAB2P Antibody

WebRecherche d’alternatives thérapeutiques aux taxanes dans les cancers de la prostate de hauts grades : Identification d’une signature prédictive de la réponse à l’oxaliplatine WebSep 26, 2024 · Orthologous to human DAB2IP (DAB2 interacting protein). [provided by Alliance of Genome Resources, Apr 2024] Other designations. disabled homolog 2-interacting protein, ASK-interacting protein 1, ASK1-interacting protein 1, DAB2-interacting protein, DOC-2/DAB-2 interactive protein, disabled 2 interacting protein …

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WebDescription: Homo sapiens DAB2 interacting protein (DAB2IP), transcript variant 1, mRNA. (from RefSeq NM_032552) RefSeq Summary (NM_032552): DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 … Web智能制造网会员企业上海谷研实业有限公司提供人蛋白激酶Cα相互作用蛋白α1（PICK1）elisa酶联免疫试剂盒介绍,人蛋白激酶Cα相互作用蛋白α1(PICK1)elisa酶联免疫试剂盒介绍的组成：的安全性：1．避免直接接触终止液和底物A、B。一旦接触到这些液 …

Disabled homolog 2-interacting protein is a protein that in humans is encoded by the DAB2IP gene. DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers (Yano et al., 2005).[supplied by OMIM] WebSep 1, 2024 · Mechanistically, DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP mRNA was down-regulated and inversely correlated with miR-1307-3p level in HCC tissues. miR-1307-3p knockdown increased the level of DAB2IP in HCC cells. Luciferase reporter assay confirmed the …

WebSep 17, 2024 · Meanwhile, the DOC-2/DAB2 interacting protein DAB2IP was previously identified as a member of the Ras-GTPase activating protein family, and functions as a … WebFeb 3, 2015 · Dab2 is an adapter protein involved in receptor-mediated signaling, endocytosis, cell adhesion, hematopoietic cell differentiation, and angiogenesis. It plays …

WebApr 1, 2002 · Human DAB2IP (for DAB2 interaction protein) is a novel member of the RasGTPase-activating protein family. It interacts directly with DAB2, which suppresses growth of many cancer types. We demonstrated that DAB2IP is often downregulated in human prostate cancer cell lines. The predicted DAB2IP protein (967 amino acids) …

WebJun 25, 2024 · Disabled homolog 2-interacting protein is a new member of the Ras GTPase-activating protein family. 26 The preferred name of DAB2IP is disabled homolog 2-interacting protein, also called ASK-interacting protein 1, ASK1-interacting protein 1, DAB2 interaction protein, DOC-2/DAB2 interactive protein, and nGAP-like protein. … cpt code ct of thoraxWebMay 18, 2010 · The N-terminal half of DAB2IP contains a protein kinase C (see 176960) conserved region-2 (C2) domain and a RasGAP domain. The C-terminal half contains a … distance from harare to guruveWebMar 21, 2024 · DAB2IP (DAB2 Interacting Protein) is a Protein Coding gene. Diseases associated with DAB2IP include Medulloblastoma and Arteriosclerosis. Among its related … distance from harare to chisumbanjeWebOct 6, 2011 · Disabled-2 (Dab2/DOC-2) is a mitogen-responsive adaptor protein required for multiple cellular functions. It is involved in many signaling pathways and plays an integral role in vesicular uptake and trafficking, modulating immune function, protein–protein interactions, cellular homeostasis and differentiation, oncogenesis, and inflammatory ... cpt code ct right shoulderWebFeb 7, 2024 · Specifically, we find that Dab2 myosin interacting region (MIR) binds myosin VI with a moderate affinity (184 nM) and single … distance from harare to chirumhanzuWebJul 15, 2016 · Overall, Dab2 acts as a scaffold protein by interacting with many, but not all, cargo receptors, and by establishing simultaneous contacts at the site of endocytosis, favoring recruitment of other adaptor proteins that are essential for endocytosis to occur. Disabled‐2, an obligatory intermediary in developmental processes distance from harare to chirunduWebdisabled homolog 2-interacting protein, ASK-interacting protein 1, DOC-2/DAB2 interactive protein, DOC2/DAB2 interactive protein GeneRIFs: Gene References Into Functions These findings suggest that Dab-2 is transiently upregulated and phosphorylated (particularly the p96 kDa isoform) in experimental autoimmune encephalomyelitis and … distance from harare to chiredzi