WebCytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores. WebThis gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke.
DYNC1I1 dynein cytoplasmic 1 intermediate chain 1 [Homo …
WebAug 26, 2024 · (c, d) Comparison of the β-propeller domains of dynein-2’s heterodimeric intermediate chains, WDR60 and WDR34 (c) with dynein-1’s homodimeric intermediate chain (IC2) (d), following alignment ... WebMay 15, 2024 · The remarkable ability of dynein to interact with a diverse cargo spectrum stems from its tightly regulated recruitment of cargo-specific adaptor proteins, which … uk roads traffic
Regulation of Flagellar Dynein by Phosphorylation of a 138-kD …
WebCytoplasmic dynein is a member of the dynein superfamily of proteins. It is a massive multisubunit complex (1.2 MD) composed of two heavy chains (∼530 kD), three intermediate chains (74 kD), and four light intermediate chains (∼55 kD), and moves along microtubules toward their minus ends (13, 23) (Fig.5). WebDynein has the same basic structures in all cell types and is composed of two or three distinct heavy chains (450 kD), three intermediate chains (70-125 kD), and at least four … WebCytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein … thompson and parkes orton