The pc12 cell as model for neurosecretion
WebbIn 1975 Tischler and Greene reported the culture of a norepinephrine producing pheochromocytoma previously observed and carried in New England Deaconess rats by … Webb25 okt. 1996 · Due to the above properties, PC12 cells have been considered since their isolation as a valuable model for neurosecretion studies. Recently, their use has become …
The pc12 cell as model for neurosecretion
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WebbThe PC12 cell line has been used to get more information about diseases of the brain. It has been used in research of hypoxia, where acute hypoxia induces exocytosis and … WebbPC12 cells contain a large number of secretory granules for storage of small molecules, processing enzymes, neuropeptides, and peptide hormones. Secretory granule exocytosis in PC12 cells is tightly regulated by calcium and occurs in response to a secretagogue (Bader et al., 2002 ).
Webb15 nov. 2007 · PC12 cells have been widely used as a model for neural differentiation and as such they have been used to examine the effects of differentiation on exocytotic … WebbDive into the research topics of 'The PC12 cell as model for neurosecretion'. Together they form a unique fingerprint. Sort by Weight Alphabetically Medicine & Life Sciences. …
WebbATP-induced inward currents were measured in mock-, wild-type or mutant (C90S)-UCH L1-transfected PC12 cells under the conventional whole-cell patch clamp configuration. The amplitude of ATP-induced currents was significantly greater in both wild-type and C90S UCH L1-transfected cells, suggesting that hydrolase activity was not involved but … Webb1. Introduction. Tumor-derived cell lines have been extensively used as models to study pathological conditions. The features of such proliferating cells—homogenous and …
WebbPC-12 cells have been widely used as a neuronal line study model in many biosensing devices, mainly due to the neurogenic characteristics acquired after differentiation, such as high level of secreted neurotransmitter, neuron morphology characterized by neurite outgrowth, and expression of ion and neurotransmitter receptors.
Webb12 apr. 2024 · PC12 cells were stimulated with increasing doses of LPS (0, 1, 2, 5, or 10 μg/mL, Cat#L2630, Sigma-Aldrich) for 12 h. 5 μg/mL was selected to mimic the model of … how many seasons of psych are thereWebb1 mars 2008 · The PC12 cell as model for neurosecretion Authors: Remco H S Westerink Utrecht University Andrew G Ewing University of Gothenburg Request full-text Abstract … how did edgar poe try to escape povertyWebb15 juni 2024 · PC-12 cell line is preferred as model in neurobiology studies because of its neurogenic characteristics (after differentiation) such as neurotransmitters secretion … how many seasons of ratchedWebb1 sep. 2007 · The catecholamine-secreting PC12 cell line derived from the rat adrenal medulla has long been considered a model system for neurosecretion and neuronal … how did edith frank dieWebbPC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla, that have an embryonic origin from the neural crest that has a mixture of neuroblastic cells and eosinophilic cells. [1] [2] [3] See something missing? how did edith die on archie bunker\u0027s placeWebb11 okt. 2013 · (A) PC12 cells were treated with LPS, culture medium of BV-2 only, or culture medium of BV-2 cocultivated with1 mg/ml LPS. Then, cell viability was assessed by MTT assay after 18 h. (B) Effects of exposure of PC12 cells to resveratrol, nicotinamide for 24 h. Then, cell viability was assessed by MTT assay. how many seasons of queen\u0027s gambitWebb21 juli 2016 · REVIEW The PC12 cell as model for neurosecretion R. H. S. Westerink 1 and A. G. Ewing 2,3 1 Cellular and Molecular Toxicology, Institute for Risk Assessment … how did edith piaf die